Beyond structure: Deciphering site‐specific dynamics in proteins from double histidine‐based EPR measurements
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4359
Abstract: Site‐specific dynamics in proteins are at the heart of protein function. While electron paramagnetic resonance (EPR) has potential to measure dynamics in large protein complexes, the reliance on flexible nitroxide labels is limitating especially for… read more here.
Keywords: dynamics proteins; specific dynamics; epr; double histidine ... See more keywords
Conformational Features and Hydration Dynamics of Proteins in Cosolvents: A Perspective from Computational Approaches
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c08009
Abstract: The importance of solvent in stabilizing protein structures has long been recognized. Water is the common solvent for proteins, and hydration is elemental in governing protein stability, flexibility, and function through various interactions. The addition… read more here.
Keywords: dynamics proteins; computational approaches; protein; hydration dynamics ... See more keywords
Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15610-4
Abstract: X-ray free-electron lasers (XFELs) enable crystallographic structure determination beyond the limitations imposed upon synchrotron measurements by radiation damage. The need for very short XFEL pulses is relieved through gating of Bragg diffraction by loss of… read more here.
Keywords: ray free; dynamics proteins; structural dynamics; free electron ... See more keywords
Dynamics of proteins with different molecular structures under solution condition
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78311-4
Abstract: Incoherent quasielastic neutron scattering (iQENS) is a fascinating technique for investigating the internal dynamics of protein. However, low flux of neutron beam, low signal to noise ratio of QENS spectrometers and unavailability of well-established analyzing… read more here.
Keywords: molecular structures; different molecular; dynamics proteins; condition ... See more keywords
Coexisting origins of subdiffusion in internal dynamics of proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Physical Review E"
DOI: 10.1103/physreve.95.062403
Abstract: Subdiffusion in conformational dynamics of proteins is observed both experimentally and in simulations. Although its origin has been attributed to multiple mechanisms, including trapping on a rugged energy landscape, fractional Brownian noise, or a fractal… read more here.
Keywords: energy landscape; dynamics proteins; coexisting origins; subdiffusion internal ... See more keywords
Targeting Mitochondrial Dynamics Proteins for the Development of Therapies for Cardiovascular Diseases
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314741
Abstract: Cardiovascular diseases are one of the leading causes of death worldwide. The identification of new pathogenetic targets contributes to more efficient development of new types of drugs for the treatment of cardiovascular diseases. This review… read more here.
Keywords: dynamics proteins; proteins development; cardiovascular diseases; mitochondrial dynamics ... See more keywords