Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B
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DOI: 10.1371/journal.pbio.3001589
Abstract: Clostridioides difficile secretes Toxin B (TcdB) as one of its major virulence factors, which binds to intestinal epithelial and subepithelial receptors, including frizzled proteins and chondroitin sulfate proteoglycan 4 (CSPG4). Here, we present cryo-EM structures… read more here.
Keywords: full length; dynamics receptor; clostridioides difficile; cspg4 ... See more keywords