The Profile and Dynamics of RNA Modifications in Animals
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DOI: 10.1002/cbic.201700093
Abstract: More than a hundred distinct modified nucleosides have been identified in RNA, but little is known about their distribution across different organisms, their dynamic nature and their response to cellular and environmental stress. Mass‐spectrometry‐based methods… read more here.
Keywords: modified nucleosides; dynamics rna; modifications animals; profile dynamics ... See more keywords
Conformational dynamics of the RNA binding channel regulates loading and translocation of the DEAH-box helicase Prp43.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad362
Abstract: The DEAH-box helicase Prp43 has essential functions in pre-mRNA splicing and ribosome biogenesis, remodeling structured RNAs. To initiate unwinding, Prp43 must first accommodate a single-stranded RNA segment into its RNA binding channel. This allows translocation… read more here.
Keywords: rna binding; dynamics rna; binding channel; helicase ... See more keywords