Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.
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DOI: 10.1016/j.cels.2018.10.010
Abstract: Viral DNA sensing is an essential component of the mammalian innate immune response. Upon binding viral DNA, the cyclic-GMP-AMP synthase (cGAS) catalyzes the production of cyclic dinucleotides to induce type I interferons. However, little is… read more here.
Keywords: dynamics uncover; cgas; interactome proteome; uncover immune ... See more keywords