Evolutionary dynamics of the Wnt gene family: implications for lophotrochozoans
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Oceanology and Limnology"
DOI: 10.1007/s00343-018-7132-7
Abstract: Genes encoding Wnt ligands, which have important roles in cell communication and organ development, are restricted to multicellular animals. We systematically studied Wnt genes from eumetazoan genomes, with emphasis on the poorly studied superphylum Lophotrochozoa… read more here.
Keywords: wnt gene; dynamics wnt; specific loss; family ... See more keywords
Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci122383
Abstract: Activating mutations in the Wnt pathway drive a variety of cancers, but the specific targets and pathways activated by Wnt ligands are not fully understood. To bridge this knowledge gap, we performed a comprehensive time-course… read more here.
Keywords: wnt; dynamics wnt; wnt dependent; dependent transcriptome ... See more keywords