Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1.
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DOI: 10.1016/j.bbrc.2018.03.189
Abstract: Balanced rates of mitochondrial division and fusion are required to maintain mitochondrial function, as well as cellular and organismal homeostasis. In mammals, the cellular machines that mediate these processes are dynamin-related GTPases; the cytosolic DRP1… read more here.
Keywords: division dynamin; mitochondrial division; division; dynamin drp1 ... See more keywords