Genetic defects in peroxisome morphogenesis (Pex11β, dynamin‐like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid‐phospholipid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12582
Abstract: Peroxisomes are essential organelles involved in lipid metabolisms including plasmalogen biosynthesis and β‐oxidation of very long‐chain fatty acids. Peroxisomes proliferate by the growth and division of pre‐existing peroxisomes. The peroxisomal membrane is elongated by Pex11β… read more here.
Keywords: docosahexaenoic acid; pex11; nucleoside diphosphate; acid ... See more keywords
Mycobacterial dynamin-like protein IniA mediates membrane fission
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DOI: 10.1038/s41467-019-11860-z
Abstract: Mycobacterium tuberculosis infection remains a major threat to human health worldwide. Drug treatments against tuberculosis (TB) induce expression of several mycobacterial proteins, including IniA, but its structure and function remain poorly understood. Here, we report… read more here.
Keywords: fission; membrane fission; like protein; inia ... See more keywords
Dynamin-like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis.
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DOI: 10.15252/embr.202255593
Abstract: Mycobacterium tuberculosis (Mtb) secretes extracellular vesicles (EVs) containing a variety of proteins, lipoproteins, and lipoglycans. While emerging evidence suggests that EVs contribute to tuberculosis pathogenesis, the factors and molecular mechanisms involved in mycobacterial EV production… read more here.
Keywords: mycobacterium tuberculosis; like proteins; tuberculosis; proteins mediate ... See more keywords
Dynamin-like Protein 1 (DNML1) as a Molecular Target for Antibody-Based Immunotherapy to Treat Glaucoma
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DOI: 10.3390/ijms232113618
Abstract: Slow and progressive loss of retinal ganglion cells (RGCs) is the main characteristic of glaucoma, the second leading cause of blindness worldwide. Previous studies have shown that impaired mitochondrial dynamics could facilitate retinal neurodegeneration. Mitochondrial… read more here.
Keywords: glaucoma; antibody based; dynamin like; protein ... See more keywords