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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09999-w
Abstract: Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are…
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Keywords:
dynein dynactin;
numa lgn;
cortical force;
lgn ... See more keywords
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Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-28952-y
Abstract: The small GTPase ARL8 associates with endolysosomes, leading to the recruitment of several effectors that couple endolysosomes to kinesins for anterograde transport along microtubules, and to tethering factors for eventual fusion with other organelles. Herein…
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Keywords:
arl8 effectors;
effectors promote;
dynein dynactin;
rufy3 rufy4 ... See more keywords
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1
Published in 2018 at "Biology Open"
DOI: 10.1242/bio.033233
Abstract: ABSTRACT Dynein is the sole processive minus-end-directed microtubule motor found in animals. It has roles in cell division, membrane trafficking, and cell migration. Together with dynactin, dynein regulates centrosomal orientation to establish and maintain cell…
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Keywords:
dynein dynactin;
cell migration;
migration;
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0209820
Abstract: Microtubules (Mts) are dynamic cytoskeleton structures that play a key role in vesicular transport. The Mts-mediated transport depends on motor proteins named kinesins and the dynein/dynactin motor complex. The Rab7 adapter protein FYCO1 controls the…
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Keywords:
dynein dynactin;
ccv;
transport;
role ... See more keywords