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Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules28010036

Abstract: The DYRK (Dual-specificity tyrosine phosphorylation-regulated kinase) family of protein kinases is involved in the pathogenesis of several neurodegenerative diseases. Among them, the DYRK1A protein kinase is thought to be implicated in Alzheimer’s disease (AD) and… read more here.

Keywords: new class; dyrk1a clk1; class; clk1 inhibitors ... See more keywords