Differential regulation of expression of the protein kinases DYRK1A and DYRK1B in cancer cells
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-74190-1
Abstract: The protein kinases DYRK1A and DYRK1B are pivotal regulators of cell cycle progression by promoting cell cycle exit into quiescence. DYRK1B appears to play a more important role in cancer cell quiescence than DYRK1A, as… read more here.
Keywords: protein kinases; cancer; dyrk1a dyrk1b; expression ... See more keywords
N-Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents
Sign Up to like & getrecommendations! Published in 2024 at "Cancers"
DOI: 10.3390/cancers16112033
Abstract: Simple Summary The demand for multitarget-directed anticancer agents has been steadily increasing, as cancer remains a leading cause of death worldwide. Dyrk and Clk kinases play crucial roles in cancer cell division and survival. Our… read more here.
Keywords: cancer; dyrk1b clk1; anticancer agents; dyrk1a dyrk1b ... See more keywords