Brain lymphatic (dys)function
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0194-z
Abstract: The discovery of brain lymphatics has challenged the concept that the healthy brain is an immunoprivileged organ; however, the function of these lymphatics in disease states has been unclear. In Nature, Kipnis and colleagues investigate… read more here.
Keywords: lymphatic dys; brain lymphatic; dys function; brain lymphatics ... See more keywords
Lysosome (Dys)function in Atherosclerosis—A Big Weight on the Shoulders of a Small Organelle
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.658995
Abstract: Atherosclerosis is a progressive insidious chronic disease that underlies most of the cardiovascular pathologies, including myocardial infarction and ischemic stroke. The malfunctioning of the lysosomal compartment has a central role in the etiology and pathogenesis… read more here.
Keywords: lysosome dys; atherosclerosis big; dys function; lysosomal compartment ... See more keywords
Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00532
Abstract: Mitochondrial dysfunction has been implicated in the pathogenesis of insulin resistance, the hallmark of type 2 diabetes mellitus (T2DM). However, the cause-effect relationship remains to be fully elucidated. Compelling evidence suggests that boosting mitochondrial function… read more here.
Keywords: insulin; mitochondrial dys; dys function; insulin resistance ... See more keywords
From the Structural and (Dys)Function of ATP Synthase to Deficiency in Age-Related Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12030401
Abstract: The ATP synthase is a mitochondrial inner membrane complex whose function is essential for cell bioenergy, being responsible for the conversion of ADP into ATP and playing a role in mitochondrial cristae morphology organization. The… read more here.
Keywords: synthase; dys function; atp synthase; structural dys ... See more keywords