Gut dysbiosis and heart failure: navigating the universe within
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1792
Abstract: Alternations in gut microbial composition (i.e. loss of microbial diversity or ‘gut dysbiosis’) have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low‐level inflammation and… read more here.
Keywords: dysbiosis; gut dysbiosis; heart failure; gut microbial ... See more keywords
Dysbiosis of the stool DNA and RNA virome in Crohn's disease
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28573
Abstract: Pathogenesis of Crohn's disease (CD) relates to gut microbiome dysbiosis. However, less is known about the viral microbiome, consisting of bacteriophages and eukaryotic viruses, in CD. Here, we profiled the stool virome, viral functions, and… read more here.
Keywords: disease; dysbiosis; crohn disease; rna virome ... See more keywords
Deoxycholic Acid-Induced Gut Dysbiosis Disrupts Bile Acid Enterohepatic Circulation and Promotes Intestinal Inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06208-3
Abstract: Background A Western diet is a risk factor for the development of inflammatory bowel disease (IBD). High levels of fecal deoxycholic acid (DCA) in response to a Western diet contribute to bowel inflammatory injury. However,… read more here.
Keywords: dysbiosis; gut dysbiosis; dca; intestinal inflammation ... See more keywords
Homeostasis and dysbiosis of the gut microbiome in health and disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biosciences"
DOI: 10.1007/s12038-019-9926-y
Abstract: The human gastrointestinal tract (GIT) harbors taxonomically and functionally complex microbial ecosystem. The composition of the microbial species in the GIT ecosystem varies among individuals and throughout development. Both environmental factors as well as host… read more here.
Keywords: dysbiosis; homeostasis; disease; git microbiome ... See more keywords
Impact of intestinal dysbiosis-related drugs on the efficacy of immune checkpoint inhibitors in clinical practice
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-020-02315-9
Abstract: Purpose Intestinal dysbiosis has emerged as a biomarker of response to immune checkpoint inhibitors (ICIs). It can be caused by antibiotics, although it may also result from the use of other drugs that have been… read more here.
Keywords: intestinal dysbiosis; immune checkpoint; dysbiosis related; dysbiosis ... See more keywords
Could the COVID-19-Driven Increased Use of Ivermectin Lead to Incidents of Imbalanced Gut Microbiota and Dysbiosis?
Sign Up to like & getrecommendations! Published in 2022 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-022-09925-5
Abstract: The microfilaricidal anthelmintic drug ivermectin (IVM) has been used since 1988 for treatment of parasitic infections in animals and humans. The discovery of IVM’s ability to inactivate the eukaryotic importin α/β1 heterodimer (IMPα/β1), used by… read more here.
Keywords: could covid; gut microbiota; dysbiosis; use ... See more keywords
Outpatient-to-Inpatient Transition Causes Marked Dysbiosis in Allogeneic Hematopoietic Cell Transplantation Recipients
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.124
Abstract: Features of gut dysbiosis such as low diversity and intestinal domination have been associated with worse outcomes after allogeneic hematopoietic cell transplantation (allo-HCT). Potential sources of insult to the microbiome vary with time. We hypothesized… read more here.
Keywords: inpatient transition; dysbiosis; transplantation; outpatient inpatient ... See more keywords
Spare and repair the gut microbiota from antibiotic-induced dysbiosis: state-of-the-art.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.02.022
Abstract: Homeostasis of the intestinal microbiota is currently recognized as a major contributor to human health. Furthermore, intestinal dysbiosis is associated with a multitude of consequences, including intestinal colonization by antibiotic-resistant or pathogenic bacteria, such as… read more here.
Keywords: dysbiosis; repair gut; microbiota; spare repair ... See more keywords
The Microbiome in Celiac Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology clinics of North America"
DOI: 10.1016/j.gtc.2018.09.008
Abstract: The healthy microbiome is necessary for normal immune development in the gut. Alterations in the microbial makeup after a critical window increase the risk of autoimmunity, including celiac disease. Although this dysbiosis has been described… read more here.
Keywords: microbiome celiac; dysbiosis; celiac disease; disease ... See more keywords
Topical anti-microbial peptide omiganan recovers cutaneous dysbiosis but does not improve clinical symptoms in patients with mild-to-moderate atopic dermatitis in a phase 2 randomized controlled trial.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.08.132
Abstract: BACKGROUND Dysbiosis and colonization with Staphylococcus aureus is considered to play an important role in the pathogenesis of atopic dermatitis (AD). Recovering this dysbiosis may improve AD symptoms. Omiganan is a synthetic indolicidin analogue antimicrobial… read more here.
Keywords: dysbiosis; treatment; atopic dermatitis; patients mild ... See more keywords
Antidepressants, antimicrobials or both? Gut microbiota dysbiosis in depression and possible implications of the antimicrobial effects of antidepressant drugs for antidepressant effectiveness.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2016.09.012
Abstract: OBJECTIVES The first drug repurposed for the treatment of depression was the tuberculostatic iproniazid. At present, drugs belonging to new classes of antidepressants still have antimicrobial effects. Dysbiosis of gut microbiota was implicated in the… read more here.
Keywords: dysbiosis; depression; antimicrobial effects; antidepressant drugs ... See more keywords