Cholecystectomy as a risk factor for metabolic dysfunction-associated fatty liver disease: unveiling the metabolic and chronobiologic clues behind the bile acid enterohepatic circulation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of physiology and biochemistry"
DOI: 10.1007/s13105-020-00782-w
Abstract: Metabolic dysfunction-associated fatty liver disease (MAFLD) is highly prevalent worldwide. Recent clinical and experimental studies have addressed the association between cholecystectomy and MAFLD, confirming that cholecystectomy is an independent risk factor for MAFLD. In this… read more here.
Keywords: fatty liver; liver disease; associated fatty; dysfunction associated ... See more keywords
Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice
Sign Up to like & getrecommendations! Published in 2022 at "Redox Biology"
DOI: 10.1016/j.redox.2022.102277
Abstract: Glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase that facilitates glutathionylation/de-glutathionylation of target proteins. The main variants of Grx2 are the mitochondrial Grx2a and the cytosolic Grx2c. The aim of this study was to investigate the… read more here.
Keywords: metabolic dysfunction; associated fatty; liver disease; fatty liver ... See more keywords
Adipose tissue dysfunction is associated with low levels of the novel Palmitic Acid Hydroxystearic Acids
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DOI: 10.1038/s41598-018-34113-3
Abstract: Adipose tissue dysfunction is considered an important contributor to systemic insulin resistance and Type 2 diabetes (T2D). Recently, a novel family of endogenous lipids, palmitic acid hydroxy stearic acids (PAHSAs), was discovered. These have anti-diabetic… read more here.
Keywords: palmitic acid; tissue dysfunction; tissue; dysfunction associated ... See more keywords
Therapeutic developments in metabolic dysfunction-associated fatty liver disease
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002091
Abstract: Abstract Metabolic dysfunction-associated fatty liver disease (MAFLD) has become one of the most prevalent chronic liver diseases worldwide, bringing risk of multiorgan disfunctions including cardiovascular events, complications of cirrhosis, and even malignance. In terms of… read more here.
Keywords: fatty liver; dysfunction associated; liver disease; associated fatty ... See more keywords
Metabolic dysfunction-associated fatty liver disease: a year in review
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Gastroenterology"
DOI: 10.1097/mog.0000000000000823
Abstract: Purpose of review In 2020, a novel comprehensive redefinition of fatty liver disease was proposed by an international panel of experts. This review aims to explore current evidence regarding the impact of this new definition… read more here.
Keywords: dysfunction associated; metabolic dysfunction; liver disease; fatty liver ... See more keywords
Metabolic dysfunction-associated fatty liver disease in obese youth with insulin resistance and type 2 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001138
Abstract: Purpose of review The aim of this review is to present the new definition of the disease, defining the epidemiology, risk factors with a particular attention to the role of insulin resistance (IR) and to… read more here.
Keywords: fatty liver; disease; insulin resistance; dysfunction associated ... See more keywords
Lean/normal‐weight metabolic dysfunction‐associated fatty liver disease is a risk factor for reflux esophagitis
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology Research"
DOI: 10.1111/hepr.13795
Abstract: Reflux esophagitis is associated with metabolic dysfunction. Recently, fatty liver has been redefined as metabolic dysfunction‐associated fatty liver disease (MAFLD). We investigated the impact of MAFLD and its subtypes on the incidence of reflux esophagitis. read more here.
Keywords: dysfunction associated; fatty liver; reflux esophagitis; metabolic dysfunction ... See more keywords
Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology Research"
DOI: 10.1111/hepr.13830
Abstract: The association between metabolic dysfunction‐associated fatty liver disease (MAFLD) and hepatocellular carcinoma (HCC) lacks clinical validation in at‐risk populations. We assessed this relationship among chronic hepatitis B (CHB) patients. read more here.
Keywords: fatty liver; chronic hepatitis; dysfunction associated; liver disease ... See more keywords
Fasting serum fructose is associated with metabolic dysfunction‐associated fatty liver disease: A prospective study
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DOI: 10.1111/hepr.13888
Abstract: The association between sugar‐sweetened beverages and metabolic disorders has been well studied. However, it has not been determined whether fasting serum fructose is associated with metabolic dysfunction‐associated fatty liver disease (MAFLD). read more here.
Keywords: associated metabolic; fasting serum; metabolic dysfunction; dysfunction associated ... See more keywords
Ferroptosis and metabolic dysfunction‐associated fatty liver disease: Is there a link?
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DOI: 10.1111/liv.15163
Abstract: Non‐alcoholic fatty liver disease (NAFLD), recently re‐defined and re‐classified as metabolic dysfunction‐associated fatty liver disease (MAFLD), has become increasingly prevalent and emerged as a public health problem worldwide. To date, the precise pathogenic mechanisms underpinning… read more here.
Keywords: fatty liver; dysfunction associated; liver disease; ferroptosis ... See more keywords
Prevalence of advanced hepatic fibrosis and comorbidity in metabolic dysfunction‐associated fatty liver disease in Korea
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DOI: 10.1111/liv.15259
Abstract: There are several reports on the prevalence of metabolic dysfunction‐associated fatty liver disease (MAFLD). However, the prevalence of advanced hepatic fibrosis in MAFLD is largely unknown. We aimed to evaluate the prevalence of advanced fibrosis… read more here.
Keywords: prevalence advanced; prevalence; dysfunction associated; fibrosis ... See more keywords