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479-P: Combination of Trans-resveratrol and Hesperetin Corrects Unscheduled Increased Glucose Metabolism Driving Dysfunction of Human Periodontal Ligament Fibroblasts in Hyperglycemia In Vitro

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Published in 2019 at "Diabetes"

DOI: 10.2337/db19-479-p

Abstract: Dysfunction of human periodontal ligament fibroblasts (PDLFs) contributes to increased prevalence and severity of periodontitis in diabetes. Hyperglycemia induces multiple pathways of metabolic dysfunction: mitochondrial dysfunction, hexosamine and protein kinase C pathway activation and increased… read more here.

Keywords: periodontal ligament; ligament fibroblasts; dysfunction human; dysfunction ... See more keywords