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Anti‐IL‐12/IL‐23p40 antibody ameliorates dermatitis and skin barrier dysfunction in mice with imiquimod‐induced psoriasis‐like dermatitis

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Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.03.018

Abstract: ABSTRACT Psoriasis is a chronic inflammatory skin disease characterized by erythema, skin hyperplasia, scales, and keratinocyte hyperproliferation. While the cause of psoriasis is not clearly understood, a dysregulated immune system, especially activation of IL‐23/IL‐17 axis,… read more here.

Keywords: dysfunction mice; barrier dysfunction; psoriasis; dermatitis ... See more keywords