Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2019.104562
Abstract: Amyotrophic lateral sclerosis (ALS) is a complex and fatal neurodegenerative disease for which the causes of disease onset and progression remain unclear. Recent advances in human induced pluripotent stem cell (hiPSC)-based models permit the study… read more here.
Keywords: dysfunction neurodegeneration; examining relationship; dysfunction; disease ... See more keywords
Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.00295
Abstract: Over the last two decades, many experimental and clinical studies have provided solid evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to Parkinson’s disease (PD) pathology. To provide an overview on… read more here.
Keywords: early synaptic; dysfunction neurodegeneration; synuclein early; synaptic dysfunction ... See more keywords