SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis
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DOI: 10.1159/000518277
Abstract: As a serious and elusive syndrome caused by infection, sepsis causes a high rate of mortality around the world. Our investigation aims at exploring the role and possible mechanism of specificity protein-1 (SP1) in the… read more here.
Keywords: sepsis; sp1; barrier dysfunction; intestinal barrier ... See more keywords
Mitochondrial Dysfunction and Oxidative Stress in Aging and Disease
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DOI: 10.3390/biomedicines10112872
Abstract: Mitochondria are considered to have a significant influence on aging due to their critical role in the regulation of bioenergetics, oxidative stress, and cell death [...]. read more here.
Keywords: stress; stress aging; aging disease; oxidative stress ... See more keywords
Mitochondrial Dysfunction and Oxidative Stress in Hereditary Ectopic Calcification Diseases
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DOI: 10.3390/ijms232315288
Abstract: Ectopic calcification (EC) is characterized by an abnormal deposition of calcium phosphate crystals in soft tissues such as blood vessels, skin, and brain parenchyma. EC contributes to significant morbidity and mortality and is considered a… read more here.
Keywords: mitochondrial dysfunction; oxidative stress; dysfunction oxidative; ectopic calcification ... See more keywords