Risks and benefits of phase I liver dysfunction studies: should patients with severe liver dysfunction be included in these trials?
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DOI: 10.1007/s10637-017-0425-4
Abstract: SummaryIntroduction The goal of organ dysfunction Phase I trials is to characterize the safety and pharmacokinetics of novel agents in cancer patients with liver or kidney dysfunction, but the clinical benefit is not well established.… read more here.
Keywords: patients severe; dysfunction; liver dysfunction; severe liver ... See more keywords