Dysfunction and toxicity of damaged proteins in the etiology of aging and age-related degenerative and malignant diseases
Sign Up to like & getrecommendations! Published in 2020 at "Croatian Medical Journal"
DOI: 10.3325/cmj.2020.61.159
Abstract: Health can be defined as a harmony, or homeostasis, of the activities of thousands of different proteins, whereas aging and diseases result from their disharmony manifested at the levels of cells and tissues. Such disharmony… read more here.
Keywords: age related; aging age; etiology; related degenerative ... See more keywords
Differential Effects of Human Tau Isoforms to Neuronal Dysfunction and Toxicity in the Drosophila CNS
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112985
Abstract: Accumulation of highly post-translationally modified tau proteins is a hallmark of neurodegenerative disorders known as tauopathies, the most common of which is Alzheimer’s disease. Although six tau isoforms are found in the human brain, the… read more here.
Keywords: tau; tau isoforms; neuronal dysfunction; dysfunction toxicity ... See more keywords