Cadmium induces mitochondrial dysfunction via SIRT1 suppression‐mediated oxidative stress in neuronal cells
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23724
Abstract: Cadmium is a widespread environmental contaminant and its neurotoxicity has raised serious concerns. Mitochondrial dysfunction is a key event in Cd‐induced nervous system disease; however, the exact molecular mechanism involved has not been fully elucidated.… read more here.
Keywords: induced mitochondrial; oxidative stress; mitochondrial dysfunction; dysfunction ... See more keywords
Glucose fluctuations promote vascular BK channels dysfunction via PKCα/NF-κB/MuRF1 signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2020.05.021
Abstract: Glucose fluctuations may contribute to large conductance calcium activated potassium (BK) channel dysfunction. However, the underlying mechanisms remain elusive. The aim of this study was to investigate the molecular mechanisms involved in BK channel dysfunction… read more here.
Keywords: dysfunction via; dysfunction; glucose fluctuations; pkc murf1 ... See more keywords
Silver ion-induced mitochondrial dysfunction via a nonspecific pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology research"
DOI: 10.1039/c7tx00079k
Abstract: Silver, once regarded as a safe noble metal for humans, has been widely used in industrial and commercial products, especially in nanometer biomaterials. It is now well known that Ag+ is biologically active and is… read more here.
Keywords: dysfunction via; silver ion; mitochondrial dysfunction; silver ... See more keywords
Rosmarinic acid protects against lipopolysaccharide‐induced cardiac dysfunction via activating Sirt1/PGC‐1α pathway to alleviate mitochondrial impairment
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13734
Abstract: Sepsis‐induced cardiomyopathy is a decisive factor that plays a critical role in the high mortality of septic patients in the critically ill. Mitochondrial dysfunction occurring during sepsis is a vital contributor to the pathogenesis of… read more here.
Keywords: rosmarinic acid; induced cardiac; dysfunction; dysfunction via ... See more keywords