Dysifragilone A inhibits LPS‑induced RAW264.7 macrophage activation by blocking the p38 MAPK signaling pathway.
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DOI: 10.3892/mmr.2017.7884
Abstract: Dysifragilone A, a sesquiterpene aminoquinone based on a rearranged avarone skeleton, has been previously isolated and identified from the South China Sea sponge Dysidea fragilis. In the present study, anti‑inflammatory activity and the underlying molecular mechanism… read more here.
Keywords: dysifragilone; raw264 macrophage; dysifragilone inhibits; activation ... See more keywords