Dysoxylactam A: A Macrocyclolipopeptide Reverses P-Glycoprotein-Mediated Multidrug Resistance in Cancer Cells.
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DOI: 10.1021/jacs.9b02259
Abstract: A 17-membered macrocyclolipopeptide, named dysoxylactam A (1) comprising an unprecedented branched C19 fatty acid and an l-valine, was isolated from the plants of Dysoxylum hongkongense. The challenging relative configuration of 1 was established by means… read more here.
Keywords: dysoxylactam macrocyclolipopeptide; resistance; cancer cells; multidrug resistance ... See more keywords