Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala.
Sign Up to like & getrecommendations! Published in 2019 at "Addiction biology"
DOI: 10.1111/adb.12813
Abstract: Administration of selective serotonin reuptake inhibitors (SSRIs), typically used as antidepressants, induces long-lasting behavioral changes associated with alcohol use disorder (AUD). However, the contribution of SSRI (fluoxetine)-induced alterations in neurobiological processes underlying alcohol relapse such… read more here.
Keywords: administration; central amygdala; relapse; dysregulates endocannabinoid ... See more keywords