Assessment of Psychosocial and Neonatal Risk Factors for Trajectories of Behavioral Dysregulation Among Young Children From 18 to 72 Months of Age
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.10059
Abstract: Key Points Question Can adverse prenatal, neonatal, and psychosocial conditions identify the earliest risk factors associated with persistent behavioral and emotional dysregulation across early childhood? Findings In this cohort study of 3934 mother-child pairs, preterm… read more here.
Keywords: behavioral dysregulation; risk factors; risk; dysregulation ... See more keywords
Revisiting CDKN2A dysregulation in Ewing sarcoma
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.70008
Abstract: Ewing sarcoma (EwS) is a rare and aggressive malignancy, which frequently affects children. One of the few recurrent genomic variants in EwS is genomic copy number deletion of CDKN2A; however, the clinical consequences of dysregulation… read more here.
Keywords: revisiting cdkn2a; cdkn2a dysregulation; dysregulation ewing; ewing sarcoma ... See more keywords
Single-Cell Dissection Reveals Immune Dysregulation After CD5 or CD7-Directed Chimeric Antigen Receptor T-Cell Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202509259
Abstract: CD5- and CD7-directed chimeric antigen receptor T-cell (5CAR and 7CAR) therapies for T-cell malignancies carry the risk of life-threatening infection. Although depletion of target-positive lymphocytes is expected, the contribution of residual cell dysfunction to infection… read more here.
Keywords: cd7 directed; therapy; cd5 cd7; cell ... See more keywords
A Supramolecular Nanoscavengers: Based "Cargo-Exchange" Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202519690
Abstract: Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM) and plays a crucial role in the development of resistance to therapeutic interventions. In this study, supramolecular nanoscavengers… read more here.
Keywords: nanoscavengers based; glioblastoma; dysregulation; supramolecular nanoscavengers ... See more keywords
Mapping the time course of overt emotion dysregulation, self‐injurious behavior, and aggression in psychiatrically hospitalized autistic youth: A naturalistic study
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2773
Abstract: Challenges with emotion dysregulation, self‐injurious behavior (SIB), and aggression are common in autistic individuals. Prior research on the relationships between these behaviors is limited mainly to cross‐sectional correlations of parent‐report data. Understanding how emotion dysregulation,… read more here.
Keywords: dysregulation; emotion dysregulation; sib aggression; overt emotion ... See more keywords
Parasympathetic withdrawal indexes risk for emotion dysregulation in children with autism spectrum disorder
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2814
Abstract: Children with autism spectrum disorder (ASD) experience significant difficulties with emotion regulation. Theory and empirical evidence suggest substantial biological contributions to regulatory challenges, which may be related to core ASD symptoms. Respiratory sinus arrythmia (RSA)… read more here.
Keywords: dysregulation children; autism; emotion dysregulation; rsa ... See more keywords
Dysregulation of the immune response in coronavirus disease 2019
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11517
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine storm in the pulmonary tissue by releasing various types of mediators, leading to acute respiratory distress syndrome (ARDS). Increased neutrophil‐to‐lymphocyte ratio, as well as… read more here.
Keywords: immune response; coronavirus disease; dysregulation; disease ... See more keywords
Mechanistic Insights Into Long Covid: Viral Persistence, Immune Dysregulation, and Multi‐Organ Dysfunction
Sign Up to like & getrecommendations! Published in 2025 at "Comprehensive Physiology"
DOI: 10.1002/cph4.70019
Abstract: Long Covid is a post‐viral syndrome characterized by persistent symptoms targeting multiple organ systems after initial SARS‐CoV‐2 infection. Current literature suggests that the mechanisms causing Long Covid involve viral persistence, immune dysregulation, systemic inflammation, endothelial… read more here.
Keywords: dysfunction; viral persistence; dysregulation; persistence immune ... See more keywords
Parent-Reported Toddler Dysregulation and Respiratory Sinus Arrhythmia Predict Trajectories of Childhood Externalizing Behaviors.
Sign Up to like & getrecommendations! Published in 2025 at "Developmental psychobiology"
DOI: 10.1002/dev.70048
Abstract: Externalizing behaviors (e.g., aggression, oppositionality, conduct problems) typically peak then decrease across early childhood (ages 2-5). However, some children continue to exhibit elevated levels of externalizing behavior throughout childhood, which can have implications for later… read more here.
Keywords: early childhood; externalizing behaviors; across early; dysregulation ... See more keywords
Impact of Sex and Salivary Dehydroepiandrosterone on the Association Between Testosterone and Emotion Dysregulation.
Sign Up to like & getrecommendations! Published in 2025 at "Developmental psychobiology"
DOI: 10.1002/dev.70053
Abstract: Adolescence is marked by changes in affect-related processing that allow individuals to learn from, and adapt to, their socioemotional environments. Although this flexibility allows for greater adaptation, it also confers unique vulnerability, marked by a… read more here.
Keywords: emotion dysregulation; emotion; psychopathology; sex ... See more keywords
Clarifying the synergistic effects of emotion dysregulation and inhibitory control on physical aggression
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26012
Abstract: Rising rates of violence underscore the need to better understand how systems that regulate distress and impulse control jointly modulate aggression risk. The goals of the current study were to investigate the unique and interactive… read more here.
Keywords: control; physical aggression; aggression; dysregulation ... See more keywords