Dysregulation of the Retromer Complex System in Down Syndrome
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DOI: 10.1002/ana.25752
Abstract: Most of the patients with Down syndrome (DS) develop Alzheimer's disease (AD) neuropathology by age 40. Although this increased susceptibility to AD in DS is thought to be primarily due to triplication of the amyloid… read more here.
Keywords: dysregulation retromer; retromer complex; complex system;