Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas
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DOI: 10.1038/s41467-020-14701-6
Abstract: Uterine leiomyomas (fibroids) are a major source of gynecologic morbidity in reproductive age women and are characterized by the excessive deposition of a disorganized extracellular matrix, resulting in rigid benign tumors. Although down regulation of… read more here.
Keywords: uterine leiomyomas; dysregulation med12; enhancer; transcriptional dysregulation ... See more keywords