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Published in 2020 at "eLife"
DOI: 10.7554/elife.58997
Abstract: LRRK2 is a kinase expressed in striatal spiny projection neurons (SPNs), cells which lose dopaminergic input in Parkinson’s disease (PD). R1441C and G2019S are the most common pathogenic mutations of LRRK2. How these mutations alter…
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Keywords:
excitatory;
specific dysregulation;
pathway specific;
lrrk2 mutations ... See more keywords