Common therapeutic advances for Duchenne muscular dystrophy (DMD)
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2020.1740218
Abstract: Abstract Background and purpose: Duchenne muscular dystrophy (DMD), a lethal X-linked recessive muscle dystrophy, is resulted in by different mutations including mostly frame-shifting gross deletions and duplications and rarely point mutations in DMD gene. Increasing… read more here.
Keywords: dmd; dystrophy dmd; muscular dystrophy; gene ... See more keywords
Myoblots: dystrophin quantification by in‐cell western assay for a streamlined development of Duchenne muscular dystrophy (DMD) treatments
Sign Up to like & getrecommendations! Published in 2018 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12448
Abstract: New therapies for neuromuscular disorders are often mutation specific and require to be studied in patient's cell cultures. In Duchenne muscular dystrophy (DMD) dystrophin restoration drugs are being developed but as muscle cell cultures from… read more here.
Keywords: dystrophy dmd; muscular dystrophy; dystrophin quantification; cell ... See more keywords
In Vitro Gene Therapy Using Human iPS-Derived Mesoangioblast-Like Cells (HIDEMs) Combined with Microdystrophin (μDys) Expression as the New Strategy for Duchenne Muscular Dystrophy (DMD) Experimental Treatment
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252211869
Abstract: Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by disruptions in the dystrophin gene. This study aims to investigate potential a therapeutic approach using genetically modified human iPS-derived mesoangioblast-like cells (HIDEMs) in mdx mouse… read more here.
Keywords: duchenne muscular; dystrophy dmd; dmd; human ips ... See more keywords