Optimization of the Linker Length in the Dimer Model of E22P-Aβ40 Tethered at Position 38.
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DOI: 10.1021/acschemneuro.2c00436
Abstract: Since amyloid β (Aβ) oligomers are more cytotoxic than fibrils, various dimer models have been synthesized. We focused on the C-terminal region that could form a hydrophobic core in the aggregation process and identified a… read more here.
Keywords: e22p; cytotoxicity; dimer; linker ... See more keywords