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Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-12-0725
Abstract: E2F8 is a transcriptional repressor that antagonizes E2F1 at the crossroads of the cell cycle, apoptosis, and cancer. Previously, we discovered that E2F8 is a direct target of the APC/C ubiquitin ligase. Nevertheless, it remains…
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Keywords:
e2f8;
proteolysis;
cell;
cycle oscillators ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21552
Abstract: A target molecule responsible for cell cycle arrest by metformin was discovered using a gene chip array in lung cancer cells and the effect of metformin on E2F8 was assessed. The siRNA-mediated knockdown of E2F8…
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Keywords:
cancer cells;
cell cycle;
lung cancer;
e2f8 ... See more keywords