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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64860-1
Abstract: Alpha1-antitrypsin (α1AT) is an abundant serine-protease inhibitor in circulation. It has an important role in neutralizing the neutrophil elastase activity. Different pathogenic point mutations like Z (E342K) -α1AT have been implicated in the development of liver…
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Keywords:
alpha1 antitrypsin;
aggregation e376d;
variant alpha1;
copd ... See more keywords