Articles with "e571k mutation" as a keyword



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Recognition of nuclear export signals by CRM1 carrying the oncogenic E571K mutation

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Published in 2020 at "Molecular Biology of the Cell"

DOI: 10.1091/mbc.e20-04-0233

Abstract: The E571K mutation of CRM1 is highly prevalent in some cancers, but its mechanism of tumorigenesis is unclear. Glu571 of CRM1 is located in its nuclear export signal (NES)-binding groove, suggesting that binding of select… read more here.

Keywords: nuclear export; crm1 e571k; crm1; e571k ... See more keywords