The Uso1 globular head interacts with SNAREs to maintain viability even in the absence of the coiled-coil domain.
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DOI: 10.7554/elife.85079
Abstract: Uso1/p115 and RAB1 tether ER-derived vesicles to the Golgi. Uso1/p115 contains a globular-head-domain (GHD), a coiled-coil (CC) mediating dimerization/tethering and a C-terminal region (CTR) interacting with golgins. Uso1/p115 is recruited to vesicles by RAB1. Genetic… read more here.
Keywords: rab1; e6k g540s; domain; ghd ... See more keywords