Self-Assembly of Spider Silk-Fusion Proteins Comprising Enzymatic and Fluorescence Activity.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00759
Abstract: The recombinant spider silk protein eADF4(C16) was genetically fused either with esterase 2 (EST2) or green fluorescent protein (GFP). The fusions EST-eADF4(C16) and GFP-eADF4(C16) were spectroscopically investigated and showed native structures of EST and GFP.… read more here.
Keywords: eadf4 c16; activity; self assembly; spider silk ... See more keywords
Recombinant Spider Silk Bioinks for Continuous Protein Release by Encapsulated Producer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00971
Abstract: Targeted therapies using biopharmaceuticals are of growing clinical importance in disease treatment. Currently, there are several limitations of protein-based therapeutics (biologicals), including suboptimal biodistribution, lack of stability, and systemic side effects. A promising approach to… read more here.
Keywords: eadf4 c16; producer; producer cells; spider silk ... See more keywords
Recombinant spider silk protein eADF4(C16)-RGD coatings are suitable for cardiac tissue engineering
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-65786-4
Abstract: Cardiac tissue engineering is a promising approach to treat cardiovascular diseases, which are a major socio-economic burden worldwide. An optimal material for cardiac tissue engineering, allowing cardiomyocyte attachment and exhibiting proper immunocompatibility, biocompatibility and mechanical… read more here.
Keywords: eadf4 c16; cardiac tissue; tissue engineering; spider silk ... See more keywords