Rbm24 regulates inner-ear-specific alternative splicing and is essential for maintaining auditory and motor coordination
Sign Up to like & getrecommendations! Published in 2020 at "RNA Biology"
DOI: 10.1080/15476286.2020.1817265
Abstract: ABSTRACT Tissue-specific alternative splicing (AS) is emerging as one of the most exciting types of mechanisms associated with organ development and disease. In the auditory system, many hearing-related genes undergo AS, and errors in this… read more here.
Keywords: rbm24; inner ear; ear specific; motor coordination ... See more keywords
A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00302-18
Abstract: Transcription factor GATA3 plays vital roles in inner ear development, while regulatory mechanisms controlling its inner ear-specific expression are undefined. We demonstrate that a cis-regulatory element lying 571 kb 3′ to the Gata3 gene directs… read more here.
Keywords: inner ear; gata3; ear specific; gata3 expression ... See more keywords