Contraceptive Use in Premenopausal Women With Early Breast Cancer
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DOI: 10.1001/jamanetworkopen.2022.33137
Abstract: Key Points Questions How do premenopausal women with early breast cancer use contraception, and what are the chosen methods and factors associated with contraceptive use? Findings In this cohort study of 2900 premenopausal women with… read more here.
Keywords: early breast; breast cancer; use; women early ... See more keywords
Adjuvant Capecitabine in Combination With Docetaxel, Epirubicin, and Cyclophosphamide for Early Breast Cancer: The Randomized Clinical FinXX Trial
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2016.6120
Abstract: Importance Capecitabine is not considered a standard agent in the adjuvant treatment of early breast cancer. The results of this study suggest that addition of adjuvant capecitabine to a regimen that contains docetaxel, epirubicin, and… read more here.
Keywords: early breast; capecitabine; docetaxel epirubicin; breast cancer ... See more keywords
Treatment With Adjuvant Abemaciclib Plus Endocrine Therapy in Patients With High-risk Early Breast Cancer Who Received Neoadjuvant Chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2022.1488
Abstract: Key Points Question Can treatment with abemaciclib provide good clinical outcomes for patients with high-risk early breast cancer who received neoadjuvant chemotherapy? Findings In this prespecified analysis of the monarchE randomized clinical trial, treatment with… read more here.
Keywords: early breast; breast; high risk; risk early ... See more keywords
Bridging the Age Gap: a prognostic model that predicts survival and aids in primary treatment decisions for older women with oestrogen receptor‐positive early breast cancer
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11748
Abstract: A prognostic model was developed and validated using cancer registry data. This underpins an online decision support tool, informing primary treatment choice for women aged 70 years or older with hormone receptor‐positive early breast cancer. read more here.
Keywords: positive early; early breast; receptor positive; prognostic model ... See more keywords
Prognostic role of immune environment in luminal B early breast cancer
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DOI: 10.1002/cam4.5642
Abstract: The importance of the immune microenvironment in triple negative and HER2‐amplified breast cancer (BC) is well‐established; less is known about the immune environment in luminal breast cancers. We aimed to assess for the impact of… read more here.
Keywords: early breast; breast; breast cancer; immune environment ... See more keywords
Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2–positive early breast cancer: Analysis from the NeoALTTO (BIG 1‐06) and ALTTO (BIG 2‐06) trials
Sign Up to like & getrecommendations! Published in 2019 at "Cancer"
DOI: 10.1002/cncr.31784
Abstract: Limited data exist on the safety of using anti–human epidermal growth factor receptor 2 (HER2) targeted agents during pregnancy. To date, only retrospective studies have assessed the prognosis of patients with a pregnancy after prior… read more here.
Keywords: early breast; factor receptor; human epidermal; growth factor ... See more keywords
Extreme hypofractionation in radiation therapy for patients with early breast cancer: what is the optimal technique?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Radiation Sciences"
DOI: 10.1002/jmrs.590
Abstract: Many radiation techniques have been employed in the trend of moving towards more hypofractionated regimens in the treatment of early breast cancer. This editorial articulates the advantages of using multi‐catheter interstitial brachytherapy when delivering extreme… read more here.
Keywords: early breast; breast; breast cancer; extreme hypofractionation ... See more keywords
Improved systemic treatment for early breast cancer improves cure rates, modifies metastatic pattern and shortens post-metastatic survival: 35-year results from the Munich Cancer Registry
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-017-2428-0
Abstract: PurposeSystemic therapies (ATHs) in early breast cancer have improved the survival of breast cancer (BC) patients in recent decades. The magnitude of the changes in overall, metastasis-free (MFS) and post-metastatic (PMS) survival and in the… read more here.
Keywords: early breast; breast cancer; post metastatic; cancer ... See more keywords
Vasomotor symptoms in early breast cancer—a “real world” exploration of the patient experience
Sign Up to like & getrecommendations! Published in 2022 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-022-06848-3
Abstract: Despite the frequency of vasomotor symptoms (VMS) in patients with early breast cancer (EBC), their optimal management remains unknown. A patient survey was performed to determine perspectives on this important clinical challenge. Patients with EBC… read more here.
Keywords: cancer; early breast; patient; breast cancer ... See more keywords
Thyroid hormone receptor beta-1 expression in early breast cancer: a validation study
Sign Up to like & getrecommendations! Published in 2018 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-018-4844-5
Abstract: PurposePreliminary data suggest that high expression of the TRβ1 tumor suppressor is associated with longer survival among women with early breast cancer. We undertook this study to validate these findings.MethodsIn this prospective cohort study, we… read more here.
Keywords: breast; early breast; study; breast cancer ... See more keywords
Prognostic effect of Ki-67 in common clinical subgroups of patients with HER2-negative, hormone receptor-positive early breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05198-9
Abstract: PurposeSeveral clinical trials have investigated the prognostic and predictive usefulness of molecular markers. With limited predictive value, molecular markers have mainly been used to identify prognostic subgroups in which the indication for chemotherapy is doubtful… read more here.
Keywords: patients her2; breast; early breast; subgroups patients ... See more keywords