Modeling EV Kinetics for Use in Early Cancer Detection
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.201900305
Abstract: Tumor‐derived extracellular vesicles (EVs) represent promising biomarkers for monitoring cancers. Technological advances have improved the ability to measure EV reliably in blood using protein, RNA, or lipid detection methods. However, it is less clear how… read more here.
Keywords: detection; early cancer; use early; modeling kinetics ... See more keywords
Graphene quantum dot-based electrochemical biosensing for early cancer detection
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Electrochemistry"
DOI: 10.1016/j.coelec.2021.100786
Abstract: Abstract Electrochemical biosensing systems coupled with graphene quantum dots (GQDs) have demonstrated suitability for cancer diagnostic strategies, particularly to identify the changes facilitating the early phases of tumorigenesis as well as to detect ultralow concentrations… read more here.
Keywords: electrochemical biosensing; cancer detection; cancer; graphene quantum ... See more keywords
Transforming the landscape of early cancer detection using blood tests—Commentary on current methodologies and future prospects
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01223-7
Abstract: Summary Early cancer detection should lead to an overall stage shift, less-intensive treatments and better patient outcomes. Current recommended screening programmes are limited to a handful of individual cancers. A multi-cancer early detection test that… read more here.
Keywords: detection; transforming landscape; cancer detection; early cancer ... See more keywords
A signal-amplifiable biochip quantifies extracellular vesicle-associated RNAs for early cancer detection
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01942-1
Abstract: Detection of extracellular vesicle (EV)-associated RNAs with low expression levels in early-stage cancer remains a challenge and is highly valuable. Here, we report a nanoparticle-based biochip that could capture circulating EVs without isolation, brighten encapsulated… read more here.
Keywords: rnas early; extracellular vesicle; early cancer; vesicle associated ... See more keywords
Clinical Practice Update: Endoscopic treatment of Barrett's esophagus with dysplasia and/or early cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2019.09.051
Abstract: DESCRIPTION The purpose of this best practice advice article is to describe, in patients with Barrett's esophagus (BE) with dysplasia/early cancer, the role of Barrett's endoscopic therapy (BET) and appropriate follow-up of these patients. METHODS… read more here.
Keywords: barrett esophagus; early cancer; practice; esophagus dysplasia ... See more keywords
Lesion-Decoupling-Based Segmentation With Large-Scale Colon and Esophageal Datasets for Early Cancer Diagnosis.
Sign Up to like & getrecommendations! Published in 2023 at "IEEE transactions on neural networks and learning systems"
DOI: 10.1109/tnnls.2023.3248804
Abstract: Lesions of early cancers often show flat, small, and isochromatic characteristics in medical endoscopy images, which are difficult to be captured. By analyzing the differences between the internal and external features of the lesion area,… read more here.
Keywords: lesion decoupling; based segmentation; segmentation; lesion ... See more keywords
Abstract 779: Clonal B-cell expansion and the potential challenges to blood-based early cancer detection
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-779
Abstract: Introduction: Confounding signals originating from white blood cells (WBCs) have been reported as a potential source of false positives for blood-based early cancer detection and disease monitoring. Additionally, the level of aberrant signal originating from… read more here.
Keywords: cancer detection; blood; early cancer; expansion ... See more keywords
Clonal evolution in healthy and premalignant tissues: implications for early cancer interception strategies.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer prevention research"
DOI: 10.1158/1940-6207.capr-22-0469
Abstract: Histologically normal human tissues accumulate significant mutational burden with age. The extent and spectra of mutagenesis are comparable both in rapidly proliferating and post-mitotic tissues and in stem cells compared to their differentiated progeny. Some… read more here.
Keywords: evolution healthy; clonal evolution; healthy premalignant; histologically normal ... See more keywords
Multi-omics analysis reveals a molecular landscape of the early recurrence and early metastasis in pan-cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1061364
Abstract: Cancer remains a formidable challenge in medicine due to its propensity for recurrence and metastasis, which can result in unfavorable treatment outcomes. This challenge is particularly acute for early-stage patients, who may experience recurrence and… read more here.
Keywords: metastasis; cancer recurrence; early cancer; recurrence metastasis ... See more keywords
Overview of Optical Biosensors for Early Cancer Detection: Fundamentals, Applications and Future Perspectives
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12020232
Abstract: Simple Summary Due to the increase in cancer incidence worldwide, a necessity for early cancer detection arises. Since the conventional detection and treatment techniques are costly, great efforts have been exerted in developing new methods… read more here.
Keywords: spectroscopy; detection; optical biosensors; cancer detection ... See more keywords