Early Clinical Expressions of Insulin Resistance: The Real Enemy to Look For
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes Therapy"
DOI: 10.1007/s13300-017-0348-2
Abstract: The type 2 diabetes mellitus epidemic threatens public healthcare systems worldwide. Efforts to prevent chronic complications of diabetes and reduce their associated mortality have been ineffective. Hence, early prevention of type 2 diabetes mellitus and… read more here.
Keywords: early clinical; type diabetes; diabetes mellitus; resistance ... See more keywords
Predictive value of the kinetics of procalcitonin and C-reactive protein for early clinical stability in patients with bloodstream infections due to Gram-negative bacteria.
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2018.07.019
Abstract: OBJECTIVE To investigate whether the magnitude of the change in procalcitonin (PCT) and C-reactive protein (CRP) levels between day 1 and day 2 after the blood culture date is associated with early clinical stability (ECS)… read more here.
Keywords: early clinical; reactive protein; clinical stability; day ... See more keywords
Early clinical experience with Guidezilla for transradial interventions in China
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23633-7
Abstract: Anatomic variations, calcified, tortuous, angulated lesions, and lack of support to increase the complexity of transradial intervention (TRI). Guidezilla is a mother-and-child catheter enabling increased support during complex interventions. As there are few published reports of… read more here.
Keywords: early clinical; guidezilla; experience guidezilla; clinical experience ... See more keywords
The early clinical development of Ebola virus treatments
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2017.1260545
Abstract: Filoviruses are highly pathogenic negative-stranded RNA hemorrhagic fever viruses. First discovered in 1967, filovirus infections in humans have increased, culminating with the recent Ebola virus epidemic in 2013–2016 that infected over 28,000 people. There are… read more here.
Keywords: clinical development; early clinical; virus; ebola virus ... See more keywords
Investigational antiarrhythmic agents: promising drugs in early clinical development
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2017.1353601
Abstract: ABSTRACT Introduction: Although there have been important technological advances for the treatment of cardiac arrhythmias (e.g., catheter ablation technology), antiarrhythmic drugs (AADs) remain the cornerstone therapy for the majority of patients with arrhythmias. Most of… read more here.
Keywords: early clinical; antiarrhythmic agents; clinical development; investigational antiarrhythmic ... See more keywords
Investigational drugs in early clinical development for portal hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2095259
Abstract: ABSTRACT Introduction Advanced chronic liver disease is considered a reversible condition after removal of the primary etiological factor. This has led to a paradigm shift in which portal hypertension (PH) is a reversible complication of… read more here.
Keywords: investigational drugs; cirrhosis; clinical development; portal hypertension ... See more keywords
Emerging epigenetic therapies of cardiac fibrosis and remodeling in heart failure: from basic mechanisms to early clinical development.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac142
Abstract: Cardiovascular diseases and specifically heart failure (HF) impact global health and impose a significant economic burden on society. Despite current advances in standard of care, the risks for death and readmission of HF patients remain… read more here.
Keywords: heart failure; development; clinical development; early clinical ... See more keywords
An Autopsy Case of Preclinical/Early Clinical Pick Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlz077
Abstract: Here, we report a 74-year-old woman with a long history of schizophrenia but no clinical manifestation of dementia. Cause of death after autopsy was atherosclerotic heart disease. Although neuropathological investigation showed no significant brain atrophy,… read more here.
Keywords: early clinical; preclinical early; disease; clinical pick ... See more keywords
Evaluation of an Infectious Diseases Elective for Early Clinical Medical Students on Their Internal Medicine Clerkship
Sign Up to like & getrecommendations! Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac120
Abstract: Abstract Background Early medical subspecialty training is an emerging trend in medical education. These electives are still rare for Early Clinical Medical Students (ECMS). We describe the introduction of an Infectious Disease (ID) inpatient consult… read more here.
Keywords: medicine; medical students; infectious diseases; early clinical ... See more keywords
1043. Evaluation of Early Clinical Failure Criteria for Gram-Negative Bloodstream Infections
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.880
Abstract: Abstract Background Early identification of patients at high risk of morbidity and mortality following Gram-negative bloodstream infections (GN-BSI) based on initial clinical course may prompt adjustments to optimize diagnostic and treatment plans. This retrospective cohort… read more here.
Keywords: early clinical; clinical failure; gram negative; mortality ... See more keywords
Early Clinical and Electrophysiological Brain Dysfunction Is Associated With ICU Outcomes in COVID-19 Critically Ill Patients With Acute Respiratory Distress Syndrome: A Prospective Bicentric Observational Study.
Sign Up to like & getrecommendations! Published in 2022 at "Critical care medicine"
DOI: 10.1097/ccm.0000000000005491
Abstract: OBJECTIVES Describe the prevalence of acute cerebral dysfunction and assess the prognostic value of an early clinical and electroencephalography (EEG) assessment in ICU COVID-19 patients. DESIGN Prospective observational study. SETTING Two tertiary critical care units… read more here.
Keywords: ill patients; critically ill; dysfunction; early clinical ... See more keywords