Neural activity mapping of bumble bee (Bombus ignitus) brains during foraging flight using immediate early genes
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DOI: 10.1038/s41598-020-64701-1
Abstract: Honey bees and bumble bees belong to the same family (Apidae) and their workers exhibit a division of labor, but the style of division of labor differs between species. The molecular and neural bases of… read more here.
Keywords: bombus ignitus; immediate early; foraging flight; flight ... See more keywords
MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression
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DOI: 10.1093/hmg/ddx099
Abstract: Mediator occupies a key role in protein coding genes expression in mediating the contacts between gene specific factors and the basal transcription machinery but little is known regarding the role of each Mediator subunits. Mutations… read more here.
Keywords: immediate early; expression; med12; genes iegs ... See more keywords
The Immunological Impact of Adenovirus Early Genes on Vaccine-Induced Responses in Mice and Nonhuman Primates
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DOI: 10.1128/jvi.02253-20
Abstract: Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Here, we provide evidence in cells, mice, and nonhuman primates supporting the notion that Ad… read more here.
Keywords: nonhuman primates; mice nonhuman; adenovirus explored; early genes ... See more keywords
Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes
Sign Up to like & getrecommendations! Published in 2019 at "BMC Microbiology"
DOI: 10.1186/s12866-019-1639-8
Abstract: BackgroundHSV-1 is a common pathogen that infects 50–90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications with activity against HSV-1. However, with the… read more here.
Keywords: hsv; immediate early; mitoxantrone dihydrochloride; early genes ... See more keywords
Retrosplenial cortex in spatial memory: focus on immediate early genes mapping
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DOI: 10.1186/s13041-021-00880-w
Abstract: The ability to form, retrieve and update autobiographical memories is one of the most fascinating features of human behavior. Spatial memory, the ability to remember the layout of the external environment and to navigate within… read more here.
Keywords: retrosplenial cortex; early genes; cortex spatial; spatial memory ... See more keywords
Cnestis ferruginea Vahl ex DC (Connaraceae) downregulates expression of immediate early genes in kainic acid-induced temporal lobe epilepsy in mice
Sign Up to like & getrecommendations! Published in 2021 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2021-0145
Abstract: Abstract Objectives This study investigates the influence of Cnestis ferruginea (CF) on kainic acid (KA)-induced immediate early genes (IEGs) associated with hippocampal sclerosis in temporal lobe epilepsy (TLE) in mice. Methods Animals were randomly divided… read more here.
Keywords: expression; kainic acid; early genes; cnestis ferruginea ... See more keywords
Skill Learning Modulates RNA Pol II Poising at Immediate Early Genes in the Adult Striatum
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DOI: 10.1523/eneuro.0074-17.2017
Abstract: Abstract A multilayered complexity of epigenetic and transcriptional regulatory mechanisms underlies neuronal activity-dependent gene transcription. The regulation of RNA Pol II progression along the transcription cycle, from promoter-proximal poising (with RNA Pol II paused at… read more here.
Keywords: immediate early; early genes; skill; learning modulates ... See more keywords
Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911637
Abstract: Antipsychotics share the common pharmacological feature of antagonizing the dopamine 2 receptor (D2R) which is abundant in the striatum and involved in both the therapeutic and side effects of this drugs class. Pharmacological blockade of… read more here.
Keywords: early genes; immediate early; action; darpp mtor ... See more keywords
Global Impairment of Immediate-Early Genes Expression in Rett Syndrome Models and Patients Linked to Myelination Defects
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DOI: 10.3390/ijms24021453
Abstract: Rett syndrome (RTT) is a severe neurodevelopmental disease caused almost exclusively by mutations to the MeCP2 gene. This disease may be regarded as a synaptopathy, with impairments affecting synaptic plasticity, inhibitory and excitatory transmission and… read more here.
Keywords: early genes; myelination; rett syndrome; immediate early ... See more keywords
Green Tea Catechins Trigger Immediate-Early Genes in the Hippocampus and Prevent Cognitive Decline and Lifespan Shortening
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DOI: 10.3390/molecules25071484
Abstract: Senescence-accelerated mouse prone 10 (SAMP10) mice, after ingesting green tea catechins (GT-catechin, 60 mg/kg), were found to have suppressed aging-related decline in brain function. The dose dependence of brain function on GT-catechin indicated that intake… read more here.
Keywords: green tea; tea catechins; immediate early; decline ... See more keywords