Mutational Processes Shaping the Genome in Early Human Embryos
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.02.008
Abstract: In-vitro-fertilized human embryos often acquire large structural and numerical chromosomal abnormalities. Liu et al. now show that multiple smaller copy number variations may also arise in in-vivo-conceived embryos. Analysis of these variations provides insight into the… read more here.
Keywords: human embryos; early human; shaping genome; genome early ... See more keywords
Microbial exposure during early human development primes fetal immune cells
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.04.039
Abstract: Summary The human fetal immune system begins to develop early during gestation; however, factors responsible for fetal immune-priming remain elusive. We explored potential exposure to microbial agents in utero and their contribution toward activation of… read more here.
Keywords: exposure; early human; exposure early; fetal immune ... See more keywords
Bioengineered pluripotent stem cell models: new approaches to explore early human embryo development.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2020.06.005
Abstract: Human development is a complex process in which environmental signals and factors encoded by the genome interact to engender cell fate changes and self-organization that drive the progressive formation of the human body. Herein, we… read more here.
Keywords: early human; stem cell; pluripotent stem; cell ... See more keywords
Fake news and post-truth pronouncements in general and in early human development.
Sign Up to like & getrecommendations! Published in 2017 at "Early human development"
DOI: 10.1016/j.earlhumdev.2017.09.017
Abstract: Fake news and post-truth pronouncements are increasingly common, and are unfortunately also progressively being applied to the sciences, including the medical sciences. This editorial briefly reviews this unsavoury trend and highlights recent debunking of fake… read more here.
Keywords: news post; post truth; human development; early human ... See more keywords
The emergence of egalitarianism in a model of early human societies
Sign Up to like & getrecommendations! Published in 2017 at "Heliyon"
DOI: 10.1016/j.heliyon.2017.e00451
Abstract: How did egalitarianism emerge in early human societies? In contrast to dominance hierarchies in non-human primates, human simple forager bands are typically egalitarian, with male hunters often serving as the collective alpha. Here we present… read more here.
Keywords: human societies; egalitarianism; early human; egalitarianism model ... See more keywords
Speleothem evidence for the greening of the Sahara and its implications for the early human dispersal out of sub-Saharan Africa
Sign Up to like & getrecommendations! Published in 2018 at "Quaternary Science Reviews"
DOI: 10.1016/j.quascirev.2018.03.016
Abstract: Abstract Although there is a consensus that there were wet periods (greening events) in the Sahara in the past, the spatial extent and the timing of these greening events are still in dispute, yet critical… read more here.
Keywords: wadi sannur; human dispersal; early human; greening sahara ... See more keywords
New Insights into Early Human Development: Lessons for Stem Cell Derivation and Differentiation.
Sign Up to like & getrecommendations! Published in 2017 at "Cell stem cell"
DOI: 10.1016/j.stem.2016.12.004
Abstract: Pathways underlying mouse embryonic development have always informed efforts to derive, maintain, and drive differentiation of human pluripotent stem cells. However, direct application of mouse embryology to the human system has not always been successful… read more here.
Keywords: insights early; early human; stem cell; differentiation ... See more keywords
Ancient African genomes offer glimpse into early human history
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/d41586-020-00167-5
Abstract: DNA sequences from children who lived in West Africa thousands of years ago might help to uncover how humans moved across the continent. DNA sequences from children who lived in West Africa thousands of years… read more here.
Keywords: genomes offer; glimpse early; offer glimpse; early human ... See more keywords
Sooner or later: does early human milk fortification improve outcomes?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Perinatology"
DOI: 10.1038/s41372-017-0013-7
Abstract: Patients: Hundred VLBW infants were allocated. Demographics were similar between groups; each group contained predominately African-American babies (90%) delivered between median of 27.5 and 28 weeks gestation primarily by C-section with median birth weight (BW)… read more here.
Keywords: early human; later early; milk fortification; human milk ... See more keywords
Through Astronaut Eyes: Photographing Early Human Spaceflight by Jennifer K. Levasseur (review)
Sign Up to like & getrecommendations! Published in 2022 at "Technology and Culture"
DOI: 10.1353/tech.2022.0038
Abstract: means of representing the world and transmitting it. It focuses on “pedagogical inventions” and the success of projection plates, which depended on the fidelity of the images produced and their “didactic effectiveness,” which in turn… read more here.
Keywords: early human; spaceflight jennifer; human spaceflight; eyes photographing ... See more keywords
Morphological variation of the early human remains from Quintana Roo, Yucatán Peninsula, Mexico: Contributions to the discussions about the settlement of the Americas
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0227444
Abstract: The human settlement of the Americas has been a topic of intense debate for centuries, and there is still no consensus on the tempo and mode of early human dispersion across the continent. When trying… read more here.
Keywords: diversity; settlement americas; early human; quintana roo ... See more keywords