Analysis of Early-Life Growth and Age at Pubertal Onset in US Children
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.46873
Abstract: This cohort study examines whether there is an association between faster growth during a child’s early life and earlier pubertal onset. read more here.
Keywords: pubertal onset; growth; early life; analysis early ... See more keywords
Burden of Infections in Early Life and Risk of Infections and Systemic Antibiotics Use in Childhood
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DOI: 10.1001/jamanetworkopen.2024.53284
Abstract: Key Points Question Does early-life infection burden track throughout childhood and into adolescence? Findings In this cohort study of 614 children with daily diary information on common infection load in early life, the overall infection… read more here.
Keywords: childhood; infections early; early life; life ... See more keywords
Early-Life Exposure to Acid-Suppressive Therapy and the Development of Celiac Disease Autoimmunity
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DOI: 10.1001/jamanetworkopen.2025.3376
Abstract: Key Points Question Is acid-suppressive therapy during early life associated with the development of celiac disease? Findings This study included both a cohort design and a test-negative case-control design. Acid-suppressive therapy was associated with celiac… read more here.
Keywords: acid suppressive; early life; celiac disease; suppressive therapy ... See more keywords
Association of Early-Life Factors With Life-Course Trajectories of Resting Heart Rate: More Than 6 Decades of Follow-up
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.5525
Abstract: Importance Higher resting heart rate (RHR) is associated with increased risk of cardiovascular and all-cause mortality. Limited attention has been paid to early-life determinants of life-course RHR. Objective To describe trajectories of RHR in the… read more here.
Keywords: rhr; age; life course; early life ... See more keywords
Reduced Oligodendrocyte Precursor Cell Impairs Astrocytic Development in Early Life Stress
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DOI: 10.1002/advs.202101181
Abstract: Abstract Astrocyte maldevelopment is implicated in various neuropsychiatric diseases associated with early life stress. However, the underlying astrocytopathy mechanism, which can result in the psychiatric symptoms, remains unclear. In this study, it is shown that… read more here.
Keywords: life stress; early life; astrocytic development;
Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202412827
Abstract: The global prevalence of Metabolic Dysfunction‐Associated Fatty Liver Disease (MAFLD) has a rising trend. The Developmental Origins of Health and Disease (DOHaD) theory assumes that MAFLD develops throughout the entire lifecycle but it originates in… read more here.
Keywords: microbiota colonization; gut microbiota; hepatic lipid; early life ... See more keywords
Season of birth and biomarkers of early‐life environment
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23532
Abstract: Early‐life conditions play an important role in human development, affecting health status and survival. Conditions in utero partly depend on the external environment and thus vary in relation to the season of birth. The aim… read more here.
Keywords: environment; early life; season birth;
Early-life behavioral features are associated with chronic emesis in rhesus macaques (Macaca mulatta)
Sign Up to like & getrecommendations! Published in 2023 at "American journal of primatology"
DOI: 10.1002/ajp.23488
Abstract: Chronic emesis (CE) is a poorly understood condition in human and nonhuman primates that negatively impacts the quality of life. Early identification of risk factors for the development of CE is likely to improve the… read more here.
Keywords: chronic emesis; macaca mulatta; early life; macaques macaca ... See more keywords
Early‐Life Adversity Predicts Markers of Aging‐Related Neuroinflammation, Neurodegeneration, and Cognitive Impairment in Women
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.27161
Abstract: Despite the overwhelming evidence for profound and longstanding effects of early‐life stress (ELS) on inflammation, brain structure, and molecular aging, its impact on human brain aging and risk for neurodegenerative disease is poorly understood. We… read more here.
Keywords: life adversity; adversity predicts; early life; neuroinflammation neurodegeneration ... See more keywords
Early life‐history adaptation influences conservation approaches for facultatively amphidromous fish
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DOI: 10.1002/aqc.3077
Abstract: Early life history is widely recognized as the stage of fish life history where mortality is the highest. Incorrect adaptation of early life‐history characteristics to environmental conditions will result in high larval mortality and therefore… read more here.
Keywords: adaptation; early life; diadromous populations; life history ... See more keywords
The impact of early‐life and prolonged antibiotics exposure on 78 common diseases: Evidence from epidemiology
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Clinical Pharmacology"
DOI: 10.1002/bcp.70055
Abstract: Early‐life and prolonged exposure to antibiotics has been associated with various health issues. This study aimed to explore the relationship between early‐life antibiotic exposure and different health outcomes from the perspective of epidemiology. read more here.
Keywords: epidemiology; prolonged antibiotics; impact early; life prolonged ... See more keywords