Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Psychiatry"
DOI: 10.1038/mp.2016.59
Abstract: A recent genome-wide association meta-analysis for Alzheimer’s disease (AD) identified 19 risk loci (in addition to APOE) in which the functional genes are unknown. Using Drosophila, we screened 296 constructs targeting orthologs of 54 candidate… read more here.
Keywords: early marker; tau; tau pathology; pathology ... See more keywords
Hyperpigmented patch: an uncommon but early marker of Wilson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-246075
Abstract: Wilson’s disease in childhood could present with features ranging from asymptomatic liver disease to acute liver failure and cirrhosis. Neurological manifestations and psychiatric illness occur more commonly in adults and older children. Skin manifestation with… read more here.
Keywords: marker wilson; disease; wilson disease; early marker ... See more keywords
Childhood generalized specific phobia as an early marker of internalizing psychopathology across the lifespan: results from the World Mental Health Surveys
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medicine"
DOI: 10.1186/s12916-019-1328-3
Abstract: BackgroundSpecific phobia (SP) is a relatively common disorder associated with high levels of psychiatric comorbidity. Because of its early onset, SP may be a useful early marker of internalizing psychopathology, especially if generalized to multiple… read more here.
Keywords: early marker; childhood; childhood generalized; marker internalizing ... See more keywords
Pseudo Hypsarrhythmia: An Early Marker of Angelman Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Indian Academy of Neurology"
DOI: 10.4103/aian.aian_413_18
Abstract: Annals of Indian Academy of Neurology ¦ Volume 22 ¦ Issue 3 ¦ July-September 2019 359 disorders. Ann Endocrinol 2007;68:173-6. 4. Patnaik SK, Upreti V, Dhull P. Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT)… read more here.
Keywords: pseudo hypsarrhythmia; early marker; hypsarrhythmia early; hashimoto encephalopathy ... See more keywords