Rural-Urban Disparities in Diagnosis of Early-Onset Dementia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.25805
Abstract: This cross-sectional study investigates differences between patients in rural and urban areas in use of cognitive assessment and treatment services for early-onset Alzheimer disease and related dementias. read more here.
Keywords: onset dementia; rural urban; early onset; urban disparities ... See more keywords
Analysis of Antibiotic Exposure and Early-Onset Neonatal Sepsis in Europe, North America, and Australia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.43691
Abstract: Key Points Question What is the rate of exposure to antibiotics and the incidence of early-onset sepsis (EOS) and sepsis-associated mortality among late-preterm and full-term newborns? Findings In this cross-sectional study of 757 979 neonates born… read more here.
Keywords: sepsis; early onset; antibiotic exposure; analysis antibiotic ... See more keywords
Evaluation of Birth by Cesarean Delivery and Development of Early-Onset Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.10316
Abstract: This case-control study conducted in Sweden examines the association between birth by cesarean delivery and development of early-onset colorectal cancer before age 50 years. read more here.
Keywords: early onset; birth cesarean; cesarean delivery; delivery development ... See more keywords
Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2021.4102
Abstract: Importance Early-onset drusen maculopathy (EODM) is a severe disease and can lead to advanced macular degeneration early in life; however, genetic and phenotypic characteristics of individuals with EODM are not well studied. Objective To identify… read more here.
Keywords: early onset; age; factor; gene ... See more keywords
Adverse Housing Conditions and Early‐Onset Delinquency
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Community Psychology"
DOI: 10.1002/ajcp.12153
Abstract: Housing constitutes an important health resource for children. Research has revealed that, when housing conditions are unfavorable, they can interfere with child health, academic performance, and cognition. Little to no research, however, has considered whether… read more here.
Keywords: early onset; onset delinquency; housing; health ... See more keywords
Early‐onset severe infections in allogeneic hematopoietic stem cell transplantation recipients with graft failure
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25406
Abstract: REFERENCES 1. Srour SA, Devesa SS, Morton LM, et al. Incidence and patient survival of myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms in the United States, 2001-12. Br J Haematol. 2016;174: 382-396. 2. Roaldsnes C, Holst R,… read more here.
Keywords: early onset; onset severe; severe infections; allogeneic hematopoietic ... See more keywords
EIF2AK2 Missense Variants Associated with Early Onset Generalized Dystonia
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Neurology"
DOI: 10.1002/ana.25973
Abstract: The study was undertaken to identify a monogenic cause of early onset, generalized dystonia. read more here.
Keywords: eif2ak2 missense; early onset; generalized dystonia; onset generalized ... See more keywords
Recessive NUP54 Variants Underlie Early‐Onset Dystonia with Striatal Lesions
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26544
Abstract: Infantile striatonigral degeneration is caused by a homozygous variant of the nuclear‐pore complex (NPC) gene NUP62, involved in nucleo‐cytoplasmic trafficking. By querying sequencing‐datasets of patients with dystonia and/or Leigh(‐like) syndromes, we identified 3 unrelated individuals… read more here.
Keywords: recessive nup54; nup54 variants; onset dystonia; early onset ... See more keywords
Responsiveness of the SARA and natural history in 884 recessive and early onset ataxia patients.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of neurology"
DOI: 10.1002/ana.26712
Abstract: OBJECTIVE The Scale for the Assessment and Rating of Ataxia (SARA) is the most widely applied clinical outcome assessment (COA) for genetic ataxias, but presents metrological and regulatory challenges. To facilitate trial planning, we characterize… read more here.
Keywords: natural history; sara; early onset; recessive early ... See more keywords
Clinical spectrum of rectal cancer identifies hallmarks of early‐onset patients and next‐generation treatment strategies
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5120
Abstract: The incidence of colorectal cancer is increasing among young adults and more rectal cancers are reported. This study aimed to identify the clinical features specific for early‐onset rectal cancer and provide insights on cancer management. read more here.
Keywords: spectrum rectal; early onset; clinical spectrum; rectal cancer ... See more keywords
Reduced expression of alanyl aminopeptidase is a robust biomarker of non‐familial adenomatous polyposis and non‐hereditary nonpolyposis colorectal cancer syndrome early‐onset colorectal cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5675
Abstract: Early‐onset colorectal cancer (EOCRC) has been increasing in incidence worldwide but its genomic pathogenesis is mostly undetermined. This study aimed to identify robust EOCRC‐specific gene expression patterns in non‐familial adenomatous polyposis (FAP) and non‐hereditary nonpolyposis… read more here.
Keywords: early onset; colorectal cancer; non familial; onset colorectal ... See more keywords