Comparison of Social Needs Among US Insured Adults Before and During the Early Phase of the COVID-19 Pandemic
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.46700
Abstract: This cross-sectional study uses survey data linked with electronic health record data to compare the prevalence of social needs among US insured adults before vs during the early phase of the COVID-19 pandemic. read more here.
Keywords: social needs; among insured; early phase; needs among ... See more keywords
Practice patterns for patients with ST‐elevation myocardial infarction during the early phase of the COVID‐19 pandemic—Valuable lessons learned
Sign Up to like & getrecommendations! Published in 2021 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.29843
Abstract: Key Points During the early phase of the COVID‐19 pandemic in the United States, there was a significant reduction in cardiac catheterization lab activations and numbers of PPCIs for STEMI as well as an increase… read more here.
Keywords: phase; early phase; practice patterns; patterns patients ... See more keywords
Biomarker changes as surrogate endpoints in early‐phase trials in heart failure with reduced ejection fraction
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13917
Abstract: No biomarker has achieved widespread acceptance as a surrogate endpoint for early‐phase heart failure (HF) trials. We assessed whether changes over time in a panel of plasma biomarkers were associated with subsequent morbidity/mortality in HF… read more here.
Keywords: heart failure; early phase; ejection fraction; heart ... See more keywords
Distinct immune responses in the early phase to natural SARS‐CoV‐2 infection or vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28034
Abstract: Immune responses elicited by viral infection or vaccination play key roles in the viral elimination and the prevention of reinfection, as well as the protection of healthy persons. As one of the most widely used… read more here.
Keywords: immune responses; infection; early phase; infection vaccination ... See more keywords
Implementation of adaptive methods in early-phase clinical trials.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.6910
Abstract: There has been constant development of novel statistical methods in the design of early-phase clinical trials since the introduction of model-based designs, yet the traditional or modified 3+3 algorithmic design remains the most widely used… read more here.
Keywords: early phase; clinical trials; implementation adaptive; phase clinical ... See more keywords
Early phase dose-finding trials in virology.
Sign Up to like & getrecommendations! Published in 2020 at "Statistics in medicine"
DOI: 10.1002/sim.8771
Abstract: Little has been published in terms of dose-finding methodology in virology. Aside from a few papers focusing on HIV, the considerable progress in dose-finding methodology of the last 25 years has focused almost entirely on… read more here.
Keywords: methodology; virology; dose finding; early phase ... See more keywords
Early‐phase risk assessments during the first epidemic year of African swine fever outbreaks in Vietnamese pigs
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.852
Abstract: Abstract Background African swine fever (ASF) is a notifiable viral disease of pigs and wild boars that could lead to serious economic losses for the swine industry. Objectives The aim of this study was to… read more here.
Keywords: early phase; risk; swine fever; outbreaks vietnamese ... See more keywords
Evolution of early phase clinical trials in oncology
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1612-7
Abstract: The therapeutic armamentarium for the treatment of cancer has rapidly evolved with the advent of molecularly targeted and immuno-oncology agents. Dramatic and prolonged responses observed in patients with advanced cancers have created excitement and promise… read more here.
Keywords: trials oncology; early phase; clinical trials; oncology ... See more keywords
Differential Response Pattern of Oropharyngeal Pressure by Bolus and Dry Swallows
Sign Up to like & getrecommendations! Published in 2017 at "Dysphagia"
DOI: 10.1007/s00455-017-9836-9
Abstract: The aim of this study was to determine if bolus and dry swallow showed similar pressure changes in the oropharynx using our newly developed device. A unique character of it includes that baropressure can be… read more here.
Keywords: phase; baropressure; early phase; bolus dry ... See more keywords
The learning effect of using stereoscopic vision in the early phase of laparoscopic surgical training for novices
Sign Up to like & getrecommendations! Published in 2017 at "Surgical Endoscopy"
DOI: 10.1007/s00464-017-5654-2
Abstract: BackgroundRecently to improve depth perception, the performance of three-dimensional (3D) laparoscopic surgeries has increased. However, the effects of laparoscopic training using 3D are still unclear. This study aimed to clarify the effects of using a… read more here.
Keywords: laparoscopic; start group; system; early phase ... See more keywords
Factors affecting symptom presentation in an early-phase clinical trials clinic patient population
Sign Up to like & getrecommendations! Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00879-0
Abstract: Increasing numbers of oncology therapies are being approved based on early-phase single-arm studies. Yet, little is known regarding the use of patient-reported outcomes in single-arm oncology trials testing novel therapies. We examined patient-reported symptom severity… read more here.
Keywords: phase; early phase; symptom severity; severity ... See more keywords