Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam
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DOI: 10.1002/epi4.12738
Abstract: We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores), considering the effect of levetiracetam,… read more here.
Keywords: plasma protein; protein biomarkers; brain; early preclinical ... See more keywords
Early preclinical evaluation of dihydropyrimidin(thi)ones as potential anticonvulsant drug candidates
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.03.014
Abstract: &NA; Although significant advances are occurring in epilepsy research, about 30% of epileptic patients are still inadequately controlled by standard drug therapy. For this reason, it continues to be important to develop new chemical entities… read more here.
Keywords: early preclinical; potential anticonvulsant; drug; dihydropyrimidin thi ... See more keywords