Articles with "early spliceosome" as a keyword



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Cooperative engagement and subsequent selective displacement of SR proteins define the pre-mRNA 3D structural scaffold for early spliceosome assembly

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac636

Abstract: We recently reported that serine-arginine-rich (SR) protein-mediated pre-mRNA structural remodeling generates a pre-mRNA 3D structural scaffold that is stably recognized by the early spliceosomal components. However, the intermediate steps between the free pre-mRNA and the… read more here.

Keywords: pre mrna; snrnp; mrna structural; structural scaffold ... See more keywords