EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification
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DOI: 10.1038/s41592-018-0037-8
Abstract: We developed EASI-tag (easily abstractable sulfoxide-based isobaric-tag), a new type of amine-derivatizing and sulfoxide-containing isobaric labeling reagents for highly accurate quantitative proteomics analysis using mass spectrometry. We observed that EASI-tag labels dissociate at low collision… read more here.
Keywords: easi tag; proteome quantification; tag enables; interference free ... See more keywords