The endothelial activation and stress index as a risk factor for all-cause mortality in patients with anemia: a nationwide retrospective cross-sectional study.
Sign Up to like & getrecommendations! Published in 2025 at "Hematology"
DOI: 10.1080/16078454.2025.2542634
Abstract: ABSTRACT Objectives Limited evidence exists on the association between the endothelial activation and stress index (EASIX) and mortality in anemia patients. This national cross-sectional study investigated the relationship between the EASIX and all-cause mortality in… read more here.
Keywords: activation stress; cause mortality; endothelial activation; easix ... See more keywords
Endothelial activation and stress index (EASIX) as a biomarker to predict ruxolitinib failure for steroid‐refractory acute graft‐versus‐host disease treatment
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DOI: 10.1111/bjh.70146
Abstract: Steroid‐refractory acute graft‐versus‐host disease (SR‐aGvHD) remains a significant challenge after haematopoietic cell transplantation (HCT). While ruxolitinib (RUX) has shown efficacy for SR‐aGvHD, failure predictors are poorly defined. We assessed 78 patients from six Canadian centres… read more here.
Keywords: easix; refractory acute; graft versus; steroid refractory ... See more keywords
Easix As Prediction Score before CAR-T Cells Vs Allogeneic Hematopoietic Cell Transplantation (alloHCT) for Relapsed/Refractory (r/r) Large B Cell Lymphoma (LBCL)
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DOI: 10.1182/blood-2020-139615
Abstract: BACKGROUND: In a previous study we have shown that CD19-directed chimeric antigen receptor (CAR)-T cells do not appear to be inferior to alloHCT when used as standard cellular immunotherapy (CI) for patients with multiply r/r… read more here.
Keywords: allohct; research funding; car; easix ... See more keywords
Easix Score Predicts Overall Survival and Non-Relapse Mortality in Elderly Patients Undergoing Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation
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DOI: 10.1182/blood-2024-212040
Abstract: Allogeneic hematopoietic cell transplantation (allo-HSCT) has seen marked growth among older adults, where chronological age is no longer a barrier to transplant. As Elderly patients are at significantly higher risk of transplantation, estimation of the… read more here.
Keywords: easix; elderly patients; log2 easix; hsct ... See more keywords
EASIX-guided risk stratification of severe coagulopathy and early mortality among newly diagnosed acute myeloid leukaemia with APL-like phenotype
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DOI: 10.1182/blood-2025-1303
Abstract: Introduction: Acute promyelocytic leukemia (APL)-like is a unique subgroup of non-M3 acute myeloid leukemia (AML), with a special CD34 and HLA-DR double-negative immunophenotype that resembles APL and common genomic alteration of NPM1 mutation. It is… read more here.
Keywords: cohort; risk apll; easix; risk ... See more keywords
Dynamic ΔEASIX score is a robust predictor of survival and relapse after allogeneic hematopoietic cell transplantation in acute leukemia
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DOI: 10.1182/blood-2025-4293
Abstract: Allogeneic hematopoietic cell transplantation (allo-HCT) remains a curative therapy for acute leukemia in transplant-eligible patients. However, post-transplant complications, including relapse and non-relapse mortality (NRM), contribute to significant transplant failure. Traditional prognostic models, which rely on… read more here.
Keywords: relapse; post transplant; easix; day ... See more keywords
Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database
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DOI: 10.1186/s40001-025-02621-4
Abstract: The Endothelial Activation and Stress Index (EASIX) is a recognized marker of vascular endothelial health but has limited application in patients with atrial fibrillation (AF). This study aimed to explore the association between EASIX and… read more here.
Keywords: cause mortality; analysis; ill patients; easix ... See more keywords
Mediation of endothelial activation and stress index in the association between vitamin B6 turnover rate and diabetic retinopathy: an analysis of the National Health and Nutrition Examination Survey
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DOI: 10.3389/fnut.2024.1490340
Abstract: Aim This study aimed to explore the association between the ratio of 4-pyridoxine (4-PA) to pyridoxal 5′-phosphate (PLP) (4-PA/PLP) and diabetic retinopathy (DR) and further assess the mediating effect of Endothelial Activation and Stress Index… read more here.
Keywords: plp; easix; analysis; mediation ... See more keywords