Ebola virus persistence as a new focus in clinical research.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2017.02.006
Abstract: Ebola virus (EBOV) causes severe acute human disease with high lethality. Viremia is typical during the acute disease phase. However, EBOV RNA can remain detectable in immune-privileged tissues for prolonged periods of time after clearance… read more here.
Keywords: ebola virus; ebov; persistence; persistence new ... See more keywords
Ebolabase: Zaire ebolavirus-human protein interaction database for drug-repurposing.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.04.184
Abstract: Ebola Virus (EBOV) is one of the deadliest pathogenic virus which causes hemorrhagic fever. Though many Ebola-human interaction studies and databases are already reported, the unavailability of an adequate model and lack of publically accessible… read more here.
Keywords: protein interaction; drug repurposing; drug; ebov ... See more keywords
Multi-template homology based structure prediction and molecular docking studies of protein ‘L’ of Zaire ebolavirus (EBOV)
Sign Up to like & getrecommendations! Published in 2017 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2017.06.002
Abstract: Abstract Ebola is one of the most dangerous pathogenic RNA virus that causes severe hemorrhagic fever in humans and is considered to be a threat to humanity. The RNA genome of EBOV encodes seven proteins… read more here.
Keywords: protein; homology based; docking studies; ebov ... See more keywords
Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2016.12.014
Abstract: There is an urgent need for Ebola virus (EBOV) proteins, EBOV-specific antibodies and recombinant antigens to be used in diagnostics and as potential vaccine candidates. Our objective was to produce and purify recombinant proteins for… read more here.
Keywords: ebola virus; ebov; ebov proteins; adjuvant system ... See more keywords
Ebola virus – prospects for a novel virus-like-particle-expressing modified vaccinia Ankara-based vaccine
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2018.1510775
Abstract: The Ebola virus (EBOV) epidemic in West Africa that devastated Guinea, Liberia, and Sierra Leone from 2013 to 2016 became a global public health crisis and claimed over 11,000 human lives [1]. There were no… read more here.
Keywords: vaccinia; ebov; mva; vaccine ... See more keywords
Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.01260-18
Abstract: Ebola virus is a genetically simple virus that has a small number of proteins. Because of this, it requires host molecules and proteins to produce new infectious virus particles. Though attention is often focused on… read more here.
Keywords: ebola virus; hypusinated eif5a; gene expression; ebov ... See more keywords
Transcriptional Analysis of Lymphoid Tissues from Infected Nonhuman Primates Reveals the Basis for Attenuation and Immunogenicity of an Ebola Virus Encoding a Mutant VP35 Protein
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.01995-20
Abstract: Zaire Ebola virus (EBOV) infection causes a severe and often fatal disease characterized by inflammation, coagulation defects, and organ failure driven by a defective host immune response. Lymphoid tissues are key sites of EBOV pathogenesis… read more here.
Keywords: response; ebola virus; infection; lymphoid tissues ... See more keywords
Modeling Ebola Virus Transmission Using Ferrets
Sign Up to like & getrecommendations! Published in 2018 at "mSphere"
DOI: 10.1128/msphere.00309-18
Abstract: Our knowledge regarding transmission of EBOV between individuals is vague and is mostly limited to spreading via direct contact with infectious bodily fluids. Studying transmission parameters such as dose and route of infection is nearly… read more here.
Keywords: transmission; direct contact; ebov; contact ... See more keywords
A Bivalent Bacterium-like Particles-Based Vaccine Induced Potent Immune Responses against the Sudan Virus and Ebola Virus in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Transboundary and Emerging Diseases"
DOI: 10.1155/2023/9248581
Abstract: Ebola virus disease (EVD) is an acute viral hemorrhagic fever disease causing thousands of deaths. The large Ebola outbreak in 2014–2016 posed significant threats to global public health, requiring the development of multiple medical measures… read more here.
Keywords: immune responses; sudv ebov; based vaccine; virus ... See more keywords
Complement-Mediated Neutralisation Identified in Ebola Virus Disease Survivor Plasma: Implications for Protection and Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.857481
Abstract: The 2013–2016 Ebola virus (EBOV) epidemic in West Africa was unprecedented in case numbers and fatalities, and sporadic outbreaks continue to arise. Antibodies to the EBOV glycoprotein (GP) are strongly associated with survival and their… read more here.
Keywords: protection; complement; neutralisation; plasma ... See more keywords
Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095228
Abstract: MicroRNAs (miRNAs) are important gene regulatory molecules involved in a broad range of cellular activities. Although the existence and functions of miRNAs are clearly defined and well established in eukaryotes, this is not always the… read more here.
Keywords: encodes two; ebola virus; virus encodes; mir ... See more keywords