Enhanced C/EBP binding to G·T mismatches facilitates fixation of CpG mutations in cancer and adult stem cells.
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DOI: 10.1016/j.celrep.2021.109221
Abstract: Somatic mutations in regulatory sites of human stem cells affect cell identity or cause malignant transformation. By mining the human genome for co-occurrence of mutations and transcription factor binding sites, we show that C/EBP binding… read more here.
Keywords: adult stem; cancer adult; ebp binding; mutations cancer ... See more keywords